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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NBEAL2 All Species: 10.3
Human Site: S2739 Identified Species: 20.61
UniProt: Q6ZNJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNJ1 NP_055990.1 2754 302517 S2739 W R S S R R I S Q V S S G E T
Chimpanzee Pan troglodytes XP_525997 2750 313008 S2735 W G S S K R L S Q I S A G E T
Rhesus Macaque Macaca mulatta XP_001094456 2295 260424 I2281 L F K S D V Y I I I E S P S L
Dog Lupus familis XP_541900 2305 251162 A2291 E P G G R A V A L I S K G G P
Cat Felis silvestris
Mouse Mus musculus Q6ZQA0 2742 301906 S2727 W R S S R R I S Q V S S G E T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508701 2269 259447 G2255 K E R K A L E G M I N N F G Q
Chicken Gallus gallus XP_421964 2298 259902 F2284 F Y R T G L H F Q Q S V E D K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4E2 3584 396477 T3468 F H S P E L I T M S R E G F I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19317 2507 281187 Q2493 E Y K H R Y I Q N T S A A K P
Sea Urchin Strong. purpuratus XP_785921 3355 375569 E3335 N T E L R I E E I L T S S K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182078 2946 321916 L2932 I I F T D P A L S L K V V D Q
Baker's Yeast Sacchar. cerevisiae P25356 2167 250854 E2153 T A E P H E I E V I A G T L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.1 40.2 74.6 N.A. 88 N.A. N.A. 39.7 40.6 N.A. N.A. N.A. 20.7 N.A. 21.1 33.4
Protein Similarity: 100 65.6 56.3 77.1 N.A. 92 N.A. N.A. 53.8 55.7 N.A. N.A. N.A. 36.1 N.A. 37.4 48.8
P-Site Identity: 100 66.6 13.3 20 N.A. 100 N.A. N.A. 0 13.3 N.A. N.A. N.A. 20 N.A. 20 13.3
P-Site Similarity: 100 93.3 20 40 N.A. 100 N.A. N.A. 20 33.3 N.A. N.A. N.A. 33.3 N.A. 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 9 9 0 0 9 17 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 17 0 0 0 0 0 0 0 0 17 9 % D
% Glu: 17 9 17 0 9 9 17 17 0 0 9 9 9 25 0 % E
% Phe: 17 9 9 0 0 0 0 9 0 0 0 0 9 9 0 % F
% Gly: 0 9 9 9 9 0 0 9 0 0 0 9 42 17 0 % G
% His: 0 9 0 9 9 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 0 0 0 9 42 9 17 42 0 0 0 0 9 % I
% Lys: 9 0 17 9 9 0 0 0 0 0 9 9 0 17 9 % K
% Leu: 9 0 0 9 0 25 9 9 9 17 0 0 0 9 17 % L
% Met: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 9 0 9 9 0 0 0 % N
% Pro: 0 9 0 17 0 9 0 0 0 0 0 0 9 0 17 % P
% Gln: 0 0 0 0 0 0 0 9 34 9 0 0 0 0 17 % Q
% Arg: 0 17 17 0 42 25 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 34 34 0 0 0 25 9 9 50 34 9 9 0 % S
% Thr: 9 9 0 17 0 0 0 9 0 9 9 0 9 0 25 % T
% Val: 0 0 0 0 0 9 9 0 9 17 0 17 9 0 0 % V
% Trp: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 0 0 0 9 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _